Selected Peer Reviewed Publications (Trainees of JZ)

  1. Stefania Echeverry, Xiang Qun Shi, Mu Yang, Hao Huang, YiChen Wu, Louis Etienne Lorenzo, Jimena Perez-Sanchez, Robert P. Bonin, Yves De Koninck, Ji Zhang (2017). Spinal microglia are required for long term maintenance of neuropathic pain Pain (accepted)
  2. Y Yao, S Echeverry, XQ Shi, M Yan, QZ Yang, GYF Wang, J Chambon, YC Wu, KY Fu, Y De Koninck, J Zhang (2016) Dynamics of spinal microglia repopulation following an acute depletion. Scientific Reports 6:22839
  3. M Rone, QL Cui, J Fang, LC Wang, D Khan, J Zhang, R Jones, G Almazan, S Ludwin, T Kennedy, and J Antel (2016) Oligodendrogliopathy in multiple sclerosis: Low glycolytic metabolic rate promotes oligodendrocyte survival. Journal of Neuroscience; 36(17):4698-707
  4. B S Mietto, A Kroner, E I Girolami,XE Santos-Nogueira, J Zhang and S David (2015) Role of IL-10 in Resolution of Inflammation and Functional Recovery after Peripheral Nerve Injury. J of Neuroscience, 35(50):16431–16442
  5. SH Lee, YS Wu, XQ Shi, J Zhang (2015) Characteristics of spinal microglia in aged and obese mice: potential contributions to impaired sensory behavior. Immunity & Ageing. Nov 24; 12:22.
  6. M Yang, C Peyret, XQ Shi, N Siron, JH Jang, S Wu, S Fournier and J Zhang (2015) Evidence from human and animal studies: Pathological roles of CD8+ T cells in autoimmune peripheral neuropathies. Frontiers in Immunology Oct 15; 6:532.
  7. TK Lim, MB Rone, S Lee, JP Antel, J Zhang. (2015) Mitochondrial and bioenergetic dysfunction in trauma-induced painful peripheral neuropathy. Mol Pain. Sep 17; 11(1):58.
  8. Sorge RE, Mapplebeck JC, Rosen S, Beggs S, Taves S, Alexander JK, Martin LJ, Austin JS, Sotocinal SG, Chen D, Yang M, Shi XQ, Huang H, Pillon NJ, Bilan PJ, Tu Y, Klip A, Ji RR, Zhang J, Salter MW, Mogil JS (2015). Different immune cells mediate mechanical pain hypersensitivity in male and female mice. Nat Neurosci. 18(8):1081-3.
  9. TK Lim, XQ Shi, JM Johnson, MB. Rone, JP. Antel, S David, J Zhang. (2015). Peripheral nerve injury induces persistent vascular dysfunction and endoneurial hypoxia, contributing to the genesis of neuropathic pain. Journal of Neuroscience 35(8):3346-59.
  10. M Yang, A Ranoine, XQ Shi, S Fournier, J Zhang (2014) A New Animal Model of Spontaneous Autoimmune Peripheral Polyneuropathy: Implications for Guillain Barré Syndrome. Acta Neuropathologica Communications, 2:5, doi:10.1186/2051-5960-2-5
  11. TKY Lim, XQ Shi, HC Martin, H Huang, G Luheshi, S Rivest, J Zhang (2014) Blood-nerve barrier dysfunction contributes to the generation of neuropathic pain and allows targeting of injured nerves for pain relief Pain, 2014, 2
  12. S Echeverry, YC WU and J Zhang (2013) Selectively reducing cytokine/chemokine expressing macrophages in injured nerves impairs the development of neuropathic pain Experimental Neurology 240:205-18
  13. JV Ragavendran, A Laferrière, WH Xiao, G Bennett, SSV Padi, J Zhang, T Coderre (2012) Topical combinations aimed at treating microvascular dysfunction reduce allodynia in rat models of CRPS-I and neuropathic pain J Pain 14(1):66-78
  14. SH Lee and J Zhang (2012) Heterogeneity of macrophages in injured trigeminal nerves: Cytokine/chemokine expressing vs. phagocytic macrophages, Brain, Behavior and Immunity 26: 891-903
  15. SSV Padi, Xiang Q Shi, Yuan Q Zhao, Michael R. Ruff, Noel Baichoo, Candace B. Pert, and Ji Zhang (2012) Attenuation of Rodent Neuropathic Pain by an Orally Active Peptide, RAP-103, which Potently Blocks CCR2 and CCR5 Mediated Monocyte Chemotaxis and Inflammation Pain 153(1): 95-106
  16. S Nadeau, M Filali, J Zhang, S Rivest, D Soulet, Y Iwakura, JP de Rivero Vaccari, RW. Keane, and S Lacroix (2011) Functional Recovery after Peripheral Nerve Injury Depends on Proinflammatory Cytokines that Mediate Pain J of Neuroscience 31 (35):12533-12542
  17. S Echeverry, XQ Shi, S Rivest, J Zhang (2011) Peripheral nerve injury alters blood spinal cord barrier functional and molecular integrity through a selective inflammatory pathway J of Neuroscience 31(30):10819-10828
  18. XQ Shi, T Lim, YQ Zhao, J Zhang (2011) Statins alleviate experimental nerve injury induced neuropathic pain Pain 152(5):1033-43
  19. SH Lee, YQ Zhao, A Ribeiro-da-Silva, J Zhang (2010) Distinctive response of CNS glial cells in oro-facial pain associated with injury, infection and inflammation Molecular Pain 6:79
  20. XQ Shi, H Zekki and J Zhang (2010) Role of TLR2 in nerve injury induced-neuropathic pain is essentially mediated through peripheral inflammatory response Glia 59: 231-241
  21. S Echeverry, XQ Shi, A Haw, L Hong, ZW Zhang, J Zhang (2009). Transforming growth factor beta1 impairs neuropathic pain through pleiotropic effect. Molecular Pain 27, 5: 16
  22. S Echeverry, XQ Shi, J Zhang (2008). Characterization of cell proliferation in rat spinal cord following peripheral nerve injury. Pain 135 (1-2): 37-47
  23. J Zhang, XQ Shi, S Echeverry, JS Mogil, Y De Koninck, S Rivest (2007) Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain. J of Neuroscience 27(45): 12396-12406
  24. J. Zhang, Y. De Koninck (2006). Spatial and temporal relationship between MCP-1 expression and spinal microglial activation following peripheral nerve injury. J.Neurochem. 97, 772-783

Reviews and Book Chapters (Trainees of JZ)

  1. J Zhang, S Echeverry, TK Lim, SH Lee, XQ Shi, H Huang. (2015). Can Modulating Inflammatory Response be a Good Strategy to Treat Neuropathic Pain? Current Pharmaceutical Research. 21(7):831-9.
  2. J Zhang. (2015) Peripheral and central immune mechanisms in neuropathic pain, Chapter 7, 109-121, Neuroinflammation: New Insights into Beneficial and Detrimental Functions, Wiley.
  3. S Echeverry, SH Lee, T Lim, J Zhang (2011) Inflammation mediates nerve injury triggered neuropathic pain In Nerve injury, InTech Open Access Publisher chapter 12, 203-214.
  4. J Zhang and Y De Koninck (2009) Central Neuroglial Interactions in the Pathophysiology of Neuropathic Pain. In Functional Chronic Pain Syndromes: Similarities and Differences in Clinical Presentation and Pathophysiology, IASP Press.
  5. RJ. Miller, W Rostene, E Apartis, G Banisadr, K Biber, ED. Milligan, FA. White, J Zhang (2008). Chemokine action in the nervous system. J of Neuroscience 28(46):11792-5
  6. J Zhang and S Echeverry (2007) Monocyte chemoattractant protein-1 and chronic pain. In Leah R. Grinwald (ed) Chemokine research trends, Novapublishers. Chapter 7, p107-120.
  7. J Zhang (2006). Involvement of monocyte chemoattractant protein-1 in peripheral nerve injury induced neuropathic pain. Reviews in Analgesia 9: 13-20.
  8. J Zhang and S Rivest (2004) Arachidonate metabolites in neurophysiological system: The fever pathway. In The Eicosanoids JohnWiley& Sons Limited. Chapter 42, 463-472.
  9. J Zhang and S Rivest (2003). Is survival possible without arachidonate metabolites in the brain during systemic infection? News in Physiological Sciences, 18:137-142.
  10. S Rivest, S Lacroix, L Valliere, S Nadeau, J Zhang and N Laflamme (2000). How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli. Proc. Soc. Exp. Biol. Med. 223 (1): 22-38.